Shop Enalapril Online | Best Prices & Deals
Enalapril: A Comprehensive Guide
Enalapril is a widely prescribed medication belonging to the class of drugs known as angiotensin-converting enzyme (ACE) inihbitors. It is primarily used to treat high blood pressure (hypertension), heart failure, and to improve survival after a heart attack.
Composition and Forms:The active ingredient is Enalapril maleate. It is available in oral tablet form, typically in strengths of 2.5 mg, 5 mg, 10 mg, and 20 mg.
Indications:- Hypertension (High Blood Pressure)
- Symptomatic congestive heart failure
- Treatment to improve survival following myocardial infarction in clinically stable patients
- Asymptomatic left ventricular dysfunction
Enalapril works by blocking the action of the angiotensin-converting enzyme. This enzyme is responsible for converting angiotensin I into angiotensin II, a potent vasoconstrictor (a substance that narrows blood vessels). By inhibiting this conversion, enalapril leads to vasodilation (widening of blood vessels), which reduces peripheral vascular resistance and lowers blood pressure. It also decreases aldosterone secretion, which helps in reducing sodium and water retention.
Safety Profile:- Benefits: Effectively lowers blood pressure, reduces the workload on the heart, and can prevent cardiovascular events like stroke and heart attack.
- Common Side Effects: May include dizziness, fatigue, headache, cough (often dry and persistent), nausea, and diarrhea.
- Serious Side Effects: Although rare, these can include angioedema (swelling of the face, lips, tongue, or throat), severe hypotension (very low blood pressure), kidney problems, and liver issues.
- Contraindications: Enalapril should not be used in patients with a history of angioedema related to previous ACE inhibitor treatment, hereditary or idiopathic angioedema, pregnancy (especially the second and third trimesters), or hypersensitivity to enalapril or other ACE inhibitors.
- Warnings: Caution is advised in patients with renal impairment, bilateral renal artery stenosis, or conditions that may increase the risk of hyperkalemia (high potassium levels). It may cause fetal harm when administered to a pregnant woman.
Dosage Table
| Condition | Recommended Dosage | Treatment Duration |
|---|---|---|
| Hypertension | Starting dose: 5-10 mg once daily. Usual maintenance dose: 10-40 mg daily in one or two divided doses. | Long-term, as prescribed by a physician. |
| Congestive Heart Failure | Starting dose: 2.5 mg once daily. Usual maintenance dose: 5-20 mg daily in two divided doses. Maximum dose: 40 mg daily. | Long-term, as prescribed by a physician. |
| Post Myocardial Infarction | Starting dose: 2.5 mg twice daily. Maintenance dose: 10 mg twice daily. | Begin within 24 hours of symptom onset; continue for at least 1 year. |
| Asymptomatic Left Ventricular Dysfunction | Starting dose: 2.5 mg twice daily. Maintenance dose: 10 mg twice daily. | Long-term, as prescribed by a physician. |
Frequently Asked Questions
Q1: How quickly does Enalapril start working?
A1: Enalapril typically begins to lower blood pressure within a few hours of taking a dose. However, it may take several days to weeks to achieve the maximum effect on blood pressure and heart failure symptoms.
Q2: Can I drink alcohol while taking Enalapril?
A2: It is generally recommended to limit or avoid alcohol consumption while taking Enalapril. Alcohol can potentiate the blood pressure-lowering effects, potentially leading to increased dizziness or lightheadedness.
Q3: What should I do if I miss a dose of Enalapril?
A3: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue witth your regular dosing schedule. Do not take a double dose to make up for a missed one.
Q4: Can Enalapril be taken with food?
A4: Yes, Enalapril can be taken with or without food. Taking it consistently at the same time each day is important for maintaining stable blood pressure levels.
