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Prevacid (Lansoprazole) Information
Prevacid, with the active ingredient lansoprazole, is a proton pump inhibitor (PPI) used to treat conditions caused by excess stomach acid. It is available in various forms, including delayed-release capsules, orally disintegrating tablets, and oral suspension.
Composition
The active ingredient in Prevacid is lansoprazole. Common dosages include 15 mg and 30 mg. It works by decreasing the amount of acid produced in the stomach.
Indications
Prevacid is prescribed for the treatment of:
- Gastroesophageal Reflux Disease (GERD)
- Erosive esophagitis associated with GERD
- Peptic ulcers (gastric and duodenal ulcers)
- Prevention of gastric ulcers in patients taking NSAIDs
- Zollinger-Ellison syndrome
- Healing of duodenal ulcers
- Heartburn associated with frequent heartburn
Mechanism of Action
Lansoprazole is a selective and non-competitive inhibitor of the H+/K+-ATPase enzyme system, commonly referred to as the 'proton pump', in gastric parietal cells. By inhibiting this pump, lansoprazole effectively blocks the final step in gastric acid production, leading to a significant reduction in both basal and stimulated gastric acid secretion, regardless of the stimulus.
Safety Profile
Benefits: Effectively reduces stomach acid, providing relief from heartburn and aiding in the healing of ulcers and esophagitis.
Potential Side Effects: Common side effects include diarrhea, constipation, nausea, stomach pain, headache, and dizziness. Less common but serious side effects can occur, such as severe allergic reactions, irregular heartbeat, and kidney problems.
Contraindications: Prevacid should not be used by individuals with known hypersensitivity to lansoprazole or any of its components.
Warnings: Long-term use of PPIs like Prevacid may be associated with an increased risk of fractures, vitamin B12 deficiency, and certain infections like C. difficile. It is important to use the lowest effective dose for the shortest duration necessary.
Dosage Table
| Condition | Dosage | Duration |
|---|---|---|
| GERD | 15 mg once daily | 4 to 8 weeks |
| Erosive Esophagitis | 30 mg once daily | Up to 8 weeks |
| Duodenal Ulcers | 15 mg once daily | 4 weeks |
| Gastric Ulcers | 30 mg once daily | Up to 8 weeks |
| Zollinger-Ellison Syndrome | 60 mg once daily | As needed, dose adjusted per patient |
| NSAID-associated Ulcers | 15-30 mg once daily | Up to 8 weeks |
Frequently Asked Questions
What is the difference between Prevacid and Prevacid 24HR?
Prevacid 24HR is a specific formulation designed to provide 24 hours of continuous acid control, typically used for frequent heartburn. Standard Prevacid dosages may vary depending on the prescribed condition and are usually taken as directed by a healthcare professional.
Can I take Prevacid with food?
For optimall absorption, Prevacid capsules and orally disintegrating tablets should be taken on an empty stomach, usually about 30 minutes to 1 hour before a meal. Check specific product instructions as they may vary.
How long does Prevacid take to start working?
While some relief may be felt within the first 24 hours, it typically takes a few days to a week for Prevacid to reach its full effect in reducing stomach acid and providing significant symptom relief.
What are the most common side effects of Prevacid?
The most frequently reported side effects are gastrointestinal issues such as diarrhea, constipation, stomach pain, and nausea. Headaches and dizziness can also occur.
