Buy Lamictal Online | Lamotrigine Medication
Lamictal (Lamotrigine) Information
Lamictal, with the active ingredient lamotrigine, is an anticonvulsant medication primarily used to treat epilepsy and bipolar disorder. It is available in various forms, including immediate-release tablets, chewable/dispersible tablets, and extended-release tablets. Generic versions are also widely available.
Indications
- Epilepsy: Adjunctive or monotherapy for partial-onset seizures, primary generalized tonic-clonic seizures, and Lennox-Gastaut syndrome in patients aged 2 years and older.
- Bipolar Disorder: Maintenance treatment for bipolar I disorder to delay mood episodes in adults and children aged 13 years and older who have been treated for bipolar disorder.
Mechanism of Action
Lamotrigine works by inhibiting voltage-gated sodium channels, which stabilizes neuronal membranes and prevents the release of excitatory neurotransmitters like glutamate. This action reduces the excessive electrical activity in the brain that can lead to seizures or mood swings.
Safety Profile
Benefits: Effective in controlling seizures and stabilizing mood in bipolar disorder. It is generally considered a well-tolerated medication when used as prescribed.
Side Effects: Common side effects include dizziness, headache, rash, nausea, blurred vision, insomnia, and fatigue. A serious, potentially life-threatening rash (Stevens-Johnson syndrome) can occur, especially with rapid dose increases or in children. It is crucial to report any rash to a doctor immediately. Other serious side effects may include aseptic meningitis and blood disorders.
Contraindications: Lamictal is contraindicated in individuals with a known hypersensitivity to lamotrigine or any of its components.
Warnings: Patients must be monitored closely for rash. Dose titration should be slow and gradual to minimize risks. Caution is advised in patients with renal or hepatic impairment. Interactions with other medications, particularly valproate and enzyme-inducing drugs like carbamazepine and phenytoin, can affect lamotrigine levels and require dose adjustments.
Dosage Table
| Condition | Adult Dosage (Starting) | Pediatric Dosage (Starting, Ages 2-12) | Maintenance Dosage |
|---|---|---|---|
| Partial-Onset Seizures (Adjunctive) | 12.5 mg once daily for 2 weeks, then 25 mg once daily for 2 weeks | (Varies by weight, consult physician) | 200-400 mg daily in 2 divided doses |
| Primary Generalized Tonic-Clonic Seizures (Adjunctive) | 12.5 mg once daily for 2 weeks, then 25 mg once daily for 2 weeks | (Varies by weight, consult physician) | 200-400 mg daily in 2 divided doses |
| Lennox-Gastaut Syndrome (Adjunctive) | 2 mg/kg/day in 2 divided doses, or 5 mg daily (whichever is lower) | (Varies by weight, consult physician) | 100-400 mg daily in 2 divided doses |
| Bipolar Disorder (Maintenance) | 25 mg once daily for 2 weeks, then 50 mg once daily for 1 week | Not approved for this indication in this age group | 100-200 mg daily in 1 or 2 divided doses |
Note: Dosage must be individualized and carefully titrated under medical supervision. The above table provides general guidelines. Always consult your healthcare provider for specific dosing instructions.
Frequently Asked Questions
- What is the most common side effct of Lamictal?
The most frequently reported side effects include dizziness, headache, rash, nausea, and fatigue. It is very important to report any skin rash to your doctor immediately, as it could be a sign of a serious reaction.
- How long does it take for Lamictal to work?
The time it takes for Lamictal to become effective varies depending on the condition being treated and the individual patient. For bipolar disorder, it's used for maintenance, meaning it helps prevent mood swings over the long term rather than providing immediate relief. For epilepsy, it may take several weeks to achieve optimal seizure control as the dose is gradually increased.
- Can I stop taking Lamictal suddenly?
No, it is strongly advised not to stop taking Lamictal abruptly. Abrupt discontinuation can lead to an increase in seizure frequency or a return of mood episodes. Your doctor will provide a plan to gradually reduce the dosage if you need to stop the medication.
- Does Lamictal cause weight gain?
Weight gain is not typically listed as a common side effect of Lamictal. Some individuals might experience changes in appetite, but significant weight gain is less common compared to some other mood stabilizers or anticonvulsants.