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Avapro (Irbesartan) - Comprehensive Information
Avapro is a prescription medication primarily used to treat high blood pressure (hypertension). It is also used to protect kidney function in patients with type 2 diabetes and hypertension.
Composition and Forms of Release
The active ingredient in Avapro is irbesartan. It belongs to a class of drugs known as angiotensin II receptor blockers (ARBs). Avapro is typically available in tablet form, with common dosages including 75 mg, 150 mg, and 300 mg of irbesartan.
Indications
Avapro is indicated for the following conditions:
- Treatment of hypertension (high blood pressure).
- Management of diabetic nephropathy (kidney disease) in patients with type 2 diabetes and hypertension.
Mechanism of Action
Irbesartan works by blocking the action of angiotensin II, a substance in the body that narrows blood vessels and raises blood pressure. By preventing angiotensin II from binding to its receptors, irbesartan causes blood vessels to relax and widen, which lowers blood pressure. This mechanism also helps to reduce strain on the kidneys, particularly in diabetic patients.
Safety Profile
Benefits: Avapro is effective in lowering blood pressure and protecting kidneys in specific patient groups. It is generally well-tolerated.
Potential Side Effects: Common side effects may include dizziness, fatigue, headache, and nausea. Less common but serious side effects can include kidney problems, severe allergic reactions, and changes in blood cell counts. Always consult your doctor if you experience persistent or bothersome side effects.
Contraindications: Avapro should not be used by individuals who are pregnant or planning to become pregnant, as it can cause harm or death to the fetus. It is also contraindicated in patients with known hypersensitivity to irbesartan or any of is inactive ingredients.
Warnings: Use with caution in patients with kidney or liver disease, heart failure, or electrolyte imbalances. Monitor kidney function and potassium levels regularly during treatment.
Dosage Table
| Condition | Recommended Dosage | Treatment Duration |
|---|---|---|
| Hypertension | 150 mg once daily | Ongoing, as prescribed by physician |
| Hypertension (severe or unresponsive) | 300 mg once daily | Ongoing, as prescribed by physician |
| Diabetic Nephropathy (Type 2 Diabetes) | 300 mg once daily | Ongoing, as prescribed by physician |
Frequently Asked Questions
Q1: How long does it take for Avapro to start working?
A: The effects of Avapro on blood pressure typically begin to show within a few days of starting treatment, with maximum effects usually seen within 2-4 weeks. Consistency in taking the medication as prescribed is key.
Q2: Can I take Avapro with other medications?
A: Avapro may interact with other drugs, including diuretics, potassium supplements, and certain pain relievers. It is crucial to inform your doctor about all medications, supplements, and herbal products you are currently taking to avoid potential interactions.
Q3: What should I do if I miss a dose of Avapro?
A: If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
Q4: Is Avapro suitable for long-term use?
A: Yes, Avapro is often prescribed for long-term management of hypertension and related kidney conditions. Your doctor will determine the appropriate duration of treatment based on your individual health status and response to the medication.