Buy Etoricoxib Online | Order Etoricoxib Tablets & Best Prices
Etoricoxib: Comprehensive Information
Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) belonging to the COX-2 inhibitor class. It is primarily used to manage pain and inflammation associated with various musculoskeletal conditions.
Composition and Forms
The active ingredient is etoricoxib. It is typically available in tablet form, with common strengths being 30 mg, 60 mg, 90 mg, and 120 mg.
Indications
Etoricoxib is prescribed for the relief of pain and inflammation in a range of conditions, including:
- Osteoarthritis (OA)
- Rheumatoid Arthritis (RA)
- Ankylosing Spondylitis (AS)
- Gouty Arthritis
- Acute pain
- Post-operative dental pain
- Symptomatic treatment of chronic low back pain
Mechanism of Action
Etoricoxib selectively inhibits the cyckooxygenase-2 (COX-2) enzyme. COX-2 is involved in the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever. By inhibiting COX-2, etoricoxib reduces the production of these prostaglandins, thereby alleviating symptoms. Unlike traditional NSAIDs which inhibit both COX-1 and COX-2, etoricoxib's selectivity aims to reduce gastrointestinal side effects associated with COX-1 inhibition.
Safety Profile
Potential Benefits:
- Effective pain relief for various inflammatory conditions.
- Lower risk of gastrointestinal complications compared to non-selective NSAIDs.
- Convenient once-daily dosing.
Potential Side Effects:
Common side effects may include edema (swelling), hypertension (high blood pressure), dizziness, headache, nausea, and diarrhea. Less common but serious side effects can include cardiovascular events (heart attack, stroke), gastrointestinal bleeding, liver problems, and allergic reactions.
Contraindications:
- Known hypersensitivity to etoricoxib or any of its excipients.
- Active peptic ulceration or active inflammatory bowel disease.
- Severe hepatic impairment.
- Patients with conditions like heart failure, established ischemic heart disease, or peripheral arterial disease.
- Pregnancy and breastfeeding.
Warnings:
Cardiovascular risk may increase with duration of use and higher doses. Caution is advised in patients with risk factors for cardiovascular disease. Patients with impaired renal function, dehydration, or heart failure should be monitored closely. Use in elderly patients may require dose adjustment.
Dosage Table
| Condition | Recommended Dosage | Treatment Duration |
|---|---|---|
| Osteoarthritis | 60 mg once daily | As needed for symptom relief |
| Rheumatoid Arthritis | 90 mg once daily | As needed for symptom relief |
| Ankylosing Spondylitis | 90 mg once daily | As needed for symptom relief |
| Gouty Arthritis (Acute) | 120 mg once daily | Maximum 8 days |
| Acute Pain | 120 mg once daily | Maximum 7 days |
| Post-operative Dental Pain | 90 mg once daily | Maximum 3 days |
| Chronic Low Back Pain | 60 mg once daily | As needed for symptom relief |
Frequently Asked Questions
Q1: How quickly does Etoricoxib start working?
A1: Pain relief typically begins within a few hours of taking the medication, with significant improvement often noted within the first few days of consistent use, depending on the condition being treated.
Q2: Can Etoricoxib be taken with food?
A2: Etoricoxib can be taken with or without food. However, taking it with food may help reduce the risk of stomach upset for some individuals.
Q3: What are the main risks associated with Etoricoxib?
A3: The main risks include potential cardiovascular events (like heart attack or stroke), especially with long-term use or in individuals with pre-existing heart conditions. Gastrointestinal issues and fluid retention can also occur.
Q4: Is Etoricoxib suitable for long-term treatment?
A4: Etoricoxib is intended for short-term or intermittent use to manage chronic pain and inflammation. The lowest effective dose should be used for the shortest duration necessary to control symptoms and minimize potential risks.