Theo-24 Cr (Theophylline Extended-Release)

Theo-24 Cr is a prescription medication containing the active ingredient theophylline, formulated as extended-release capsules. It belongs to a class of drugs known as methylxanthines, which act as bronchodilators.

Composition and Forms

The active ingredient is theophylline. Theo-24 Cr is available in extended-release capsule form, designed to release the medication slowly over a 24-hour period.

Indications

Theo-24 Cr is primarily prescribed for the symptomatic relief of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It is also used in the management of asthma and bronchospasm.

Mechanism of Action

Theophylline works by relaxing the smooth muscles in the airways of the lungs, leading to bronchodilation. It also has mild anti-inflammatory effects and can increase respiratory muscle strength. The exact mechanisms are complex but involve phosphodiesterase inhibition, leading to increased intracellular cyclic AMP, and antagonism of adenosine receptors.

Safety Profile

Potential Benefits: Theo-24 Cr can significantly improve breathing in patients with COPD and asthma by opening up airways and reducing symptom like wheezing and shortness of breath. The extended-release formulation allows for less frequent dosing, improving patient compliance.

Common Side Effects: Nausea, vomiting, headache, insomnia, irritability, restlessness, increased heart rate, and heartburn are among the more common side effects. These are often dose-related.

Contraindications: Theo-24 Cr should not be used in patients with a known hypersensitivity to theophylline or other methylxanthines. It is also contraindicated in individuals with certain cardiac arrhythmias.

Warnings: Caution is advised in patients with seizure disorders, hypertension, heart failure, liver o kidney disease, and in the elderly. Therapeutic drug monitoring is often recommended to maintain blood levels within the effective and safe range, as theophylline has a narrow therapeutic index.

Dosage Table

Note: Dosages must be individualized and adjusted based on patient response, tolerance, and serum theophylline levels. Initial dosage and titration should be determined by a healthcare professional.

Frequently Asked Questions

What is the difference between Theo-24 Cr and other theophylline formulations?

Theo-24 Cr is an extended-release formulation, meaning it is designed to release the medication slowly over a 24-hour period. This allows for once-daily dosing, which can be more convenient and lead to more stable blood levels compared to immediate-release or sustained-release formulations that may require multiple daily doses.

How should Theo-24 Cr be taken?

Theo-24 Cr capsules should be swallowed whole with a full glass of water and should not be crushed, chewed, or broken. They can be taken with or without food, but consistency in taking the medication with respect to meals is recommended for optimal absorption. Always follow your doctor's specific instructions regarding dosage and timing.

What should I do if I miss a dose of Theo-24 Cr?

If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Consult your healthcare provider if you are unsure or havE missed multiple doses.

Can Theo-24 Cr be taken with other medications?

Theo-24 Cr can interact with many other medications, including certain antibiotics, antivirals, seizure medications, and heart medications. It is crucial to inform your doctor about all medications, including over-the-counter drugs and herbal supplements, that you are currently taking to avoid potential interactions.