Buy Requip (Ropinirole) Online | Prescription Medication Deals
Requip (Ropinirole) Information
Requip, with the active ingredient Ropinirole, is a non-ergoline dopamine agonist primarily used to treat Parkinson's disease and Restless Legs Syndrome (RLS). It is available in immediate-release and extended-release formulations.
Composition
- Active Ingredient: Ropinirole
- Forms of Release:
- Immediate-Release Tablets (e.g., Requip 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg)
- Extended-Release Tablets (e.g., Requip XL 2 mg, 4 mg, 6 mg, 8 mg)
Indications
Requip is prescribed for:
- Parkinson's Disease: Management of signs and symptoms of idiopathic Parkinson's disease, used as monotherapy or in combination with levodopa.
- Restless Legs Syndrome (RLS): Treatment of moderate-to-severe primary RLS.
Mechanism of Action
Ropinirole works by stimulating dopamine receptors in the brain, specifically the D2 and D3 receptors. Dopamine is a neurotransmitter that plays a crucial role in controlling movement. In Parkinson's disease, there is a deficiency of dopamine-producing neurons. By mimickingg dopamine's action, Ropinirole helps to alleviate the motor symptoms associated with the disease, such as stiffness, tremors, and slowness of movement. In RLS, the exact mechanism is not fully understood, but it is believed to involve dysfunction in the brain's dopamine pathways.
Safety Profile
Potential Benefits: Requip can significantly improve motor function in Parkinson's patients and reduce the uncomfortable sensations associated with RLS, leading to better quality of life.
Potential Side Effects: Common side effects include nausea, vomiting, dizziness, drowsiness, fatigue, headache, and hallucinations. Less common but serious side effects can include impulse control disorders (e.g., compulsive gambling, shopping, eating, or hypersexuality), orthostatic hypotension (a drop in blood pressure upon standing), and somnolence (sudden onset of sleep). Patients should be monitored for these effects.
Contraindications: Requip is contraindicated in patients with known hypersensitivity to ropinirole or any of its inactive ingredients.
Warnings:
- Patients should be advised to report any new or worsening compulsive behaviors to their healthcare provider.
- Sudden onset of sleep may occur without warning; patients should exercise caution when driving or operating machinery.
- Use with caution in patients with severe hepatic or renal impairment.
- Pregnancy and lactation: Safety has not been established.
Dosage Table
| Condition | Dosage Form | Starting Dose | Titration Schedule | Maximum Dose | Treatment Duration |
|---|---|---|---|---|---|
| Parkinson's Disease (Early) | Immediate-Release Tablets | 0.25 mg TID | Increase by 0.25 mg/day per week | 3 mg TID | Ongoing, as needed |
| Parkinson's Disease (Advanced) | Immediate-Release Tablets | 0.5 mg TID | Increase by 0.5 mg/day per week | Up to 8 mg TID | Ongoing, as needed |
| Parkinson's Disease | Extended-Release Tablets (XL) | 2 mg Once Daily | Increase by 2 mg/day per week | 8 mg Once Daily | Ongoing, as needed |
| Restless Legs Syndrome (RLS) | Immediate-Release Tablets | 0.25 mg Once Daily (taken at bedtime) | Increase by 0.25 mg/day per week | Up to 0.75 mg once daily | As needed for symptom relief |
| Restless Legs Syndrome (RLS) | Extended-Release Tablets (XL) | 2 mg Once Daily (taken at bedtime) | Increase by 2 mg/day per week, if necessary | Up to 6 mg once daily | As needed for symptom relief |
Note: Dosage should be individualized based on patient response and tolerance. Titration schedules are general guidelines.
Frequently Asked Questions
- Can Requip be taken with food?
Requip immediate-release tablets can be taken with or without food. However, taking it with food may help reduce nausea. Requip XL should be taken once daily, with or without food, at approximately the same time each day.
- What are the most common side effects of Requip?
The most common side effects include nausea, dizziness, drowsiness, and leg swelling. It is important to discuss any side effects with your doctor.
- How long does it take for Requip to work?
For Parkinson's disease, improvements may be noticed within a few weeks of starting treatment. For RLS, symptom relief can often be experienced within days of starting the medication.
- Can I stop aking Requip suddenly?
It is generally not recommended to stop Requip suddenly, especially if you have Parkinson's disease, as this can worsen symptoms. Consult your doctor before discontinuing the medication.
