Buy Atomoxetine Online | Atomoxetine Hydrochloride Prices & Deals
Atomoxetine Hydrochloride: A Comprehensive Overview
Atomoxetine hydrochloride is a selective norepinephrine reuptake inhibitor (SNRI) primarily prescribed for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD). Unlike stimulant medications, atomoxetine is a non-stimulant, meaning it does not have the same potential for abuse or dependence.
Composition and Forms
The active ingredient is atomoxetine hydrochloride. It is typically available in delayed-release caapsules in various strengths, such as 10 mg, 18 mg, 25 mg, 40 mg, 60 mg, 80 mg, and 100 mg. The delayed-release formulation ensures that the medication is released gradually throughout the day.
Indications
Atomoxetine is FDA-approved for the treatment of ADHD in children, adolescents, and adults. It is used to help manage symptoms such as inattention, impulsivity, and hyperactivity. It can be used as a standalone treatment or in combination with behavioral therapy.
Mechanism of Action
Atomoxetine works by selectively blocking the reuptake of norepinephrine, a neurotransmitter, in the brain. Norepinephrine plays a crucial role in attention, impulse control, and executive functions. By increasing the levels of norepinephrine in the synaptic cleft, atomoxetine enhances noradrenergic neurotransmission, which is believed to improve ADHD symptoms. It does not affect dopamine reuptake significantly, distinguishing it from stimulant ADHD medications.
Safety Profile
Potential Benefits:
- Non-stimulant, reducing risk of abuse and dependence.
- Can be effective for both inattentive and hyperactive/impulsive symptoms.
- Long-acting, allowing for once-daily dosing.
Potential Side Effects:
Common side effects include:
- Nausea, vomiting, and stomach pain
- Decreased appetite
- Dry mouth
- Dizziness
- Fatigue or somnolence
- Insomnia
- Urinary hesitancy or retention
- Increased heart rate and blood pressure
Less common but serious side effects may include:
- Liver problems (rare)
- Cardiovascular effects (e.g., palpitations, syncope)
- Suicidal thoughts or behavior (especially in children and adolescents)
- Aggressive behavior or hostility
- Priapism (prolonged erection)
Contraindications:
- Hypersensitivity to atomoxetine or any of its components.
- Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing an MAOI.
- Severe cardiovascular conditions.
- Narrow-angle glaucoma.
Warnings:
Atomoxetine carries a boxed warning regarding the increased risk of suicidal thoughts and behaviors in children and adolescents. Healthcare providers should monitor patients closely for any changes in mood or behavior. It can also cause significant liver injury, and patients experiencing symptoms of liver problems should discontinue the medication and seek medical attention. Caution is advised in patients with hypertension, tachycardia, or other cardiovascular issues.
Dosage Table
| Condition | Recommended Starting Dose (mg/day) | Maximum Dose (mg/day) | Treatment Duration |
|---|---|---|---|
| ADHD in Children (<70 kg) | 0.5 mg/kg/day | 1.2 mg/kg/day (max 100 mg) | As directed by physician |
| ADHD in Children (≥70 kg) & Adults | 40 mg/day | 100 mg/day | As directed by physician |
Note: Dosing should be individualized based on patient response and tolerability. It may take several weeks for the full therapeutic effect to be observed.
Frequently Asked Questions
1. How long does it take for atomoxetine to start working?
It typically takes several weeks (usually 2-4 weeks) of consistent daily use to notice the full benefits of atomoxetine. Initial improvements may be subtle and gradually become more apparent.
2. Can atomoxetine be taken with food?
Yes, atomoxetine capsules can be taken with or without food. However, taking it with food may help reduce potential stomach upset or nausea.
3. What should I do if I miss a dose of atomoxetine?
If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. Do not take a double dose to make up for a missed dose. If you are unsure, consult your doctor or pharmacist.
4. Can atomoxetine be used for anxiety disorders?
Atomoxetine is primarily approved for ADHD. While some individuals may experience a reduction in anxiety symptoms as their ADHD improves, it is not specifically indicated or approved for the primary treatment of anxiety disorders.